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Sigma Life Science Releases Pioneering Range Of Engineered Mammalian Cell Lines - Quick Facts

(RTTNews) - Sigma-Aldrich Corp. (SIAL) Thursday said it released a pioneering range of engineered mammalian cell lines. This new product range combines Sigma's proprietary CompoZr zinc finger nuclease technology with the company's extensive experience in gene silencing, to offer innovative tools for drug discovery, compound screening and fundamental research applications.

The company noted that the zinc finger nuclease technology enables scientists to generate precisely controlled additions, deletions and modifications to the genome of a living cell. Dr. Supriya Shivakumar, Global Commercial Marketing Manager for Functional Genomics at Sigma Life Science said, "Leveraging this innovative and powerful technology to develop ready-to-use, validated cell lines is part of Sigma's ongoing commitment to furthering our understanding of biology."

The program will use ZFNs to incorporate and develop cell lines with a variety of cellular markers expected to aid in compound screening studies and biochemical pathway analysis, as well as specific isogenic lines designed to advance colorectal and breast cancer research. In addition, Sigma offers a custom cell line engineering service, creating bespoke cell lines to perfectly match a researcher's application.